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In contrast, a typical dendritic channel has no myelination and is continuously active all along its path In an axon, small losses because of resistance and conductance are compensated by the In sources available through the exposed membrane at the nodes of Ranvier, so that pulses propagate without appreciable attenuation Since rise and fall times are slow, in the millisecond range, losses in series resistance are very small, as shown in the appendix to this chapter A loss in the conductance at a node of Ranvier is very small because the area exposed is very small Conductive energy losses occur not only in the nodes of Ranvier, but in the soma and dendrites, where myelination is absent Such losses are common to all neurons and indeed to all cells in the body and are considered a normal part of cellular maintenance.

Specify length of segment or [Block]:B Enter name of block to insert:TOILET Align block with object [Yes/No]:~ Specify length of segrnent:1000

They have little or nothing to do with neural signals, which seem to utter back and forth in an electrically reversible way without the dissipation of appreciable energy The diameters of an axon are continually decreasing, such that Cn 1WCnWCn + 1 This has certain practical implications If a stray photon causes a charge to appear in Cn, it is unlikely that it will trigger an action potential This is because the charge will soon be shared with Cn 1 and Cn + 1 By conservation of charge, charge is divided, and in the nodes of Ranvier, voltage is expected to be well below a triggering threshold for Cn 1 and Cn + 1 Thus, a stray cosmic ray probably could not begin an action potential in a reliable neuron Pulses go down an axon readily but are not re ected or otherwise returned to the hillock and soma.

FIGURE 6-16

7.75 For the underdamped circuit shown in Fig. P7.75, determine the voltage v( t) if the initial condi tions on the storage clements arc iJO) I A and v,(O) = 10 V.

This cannot occur because an axon terminates in a bouton, an organ that develops without a source of energy to trigger a back propagation Also, it is dif cult for a signal to move from a smaller capacitance Cn 1 to a larger capacitance Cn with enough voltage to trigger a node of Ranvier and gain enough charge for an even larger capacitance, Cn + 1 The computerized simulation given in 5 indicates that no re ections are possible from the ends of a neuron, with or without myelination In contrast, back propagations (re ections) from dendritic junctions as well as from the soma appear to be quite normal As a result of a soma pulse, for the purposes of this discussion, Cs may be thought of as holding an excess voltage of about 100 mV (a rounded-off value; the model above used 110 mV).

To add layers by selecting objects that are on the layers you want, right-click the filter and choose Select Layers Add. You return to your drawing where you can select objects. Press Enter to end object selection.

The net magnitude of soma capacitance Cs is surprisingly large Using a sphere with.

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